THE SEPARATION OF BIOLOGICAL STAINS BY FILTER PAPER ELECTROPHORESIS

The separation of esters of choline by filter-paper chromatography.

7. It is concluded that tran8-tran8-muconic acid is probably a true metabolite of benzene and is not produced in vivo from the ci8-ci8-acid. It is suggested that the 68-c68-acid need not be an intermediate in the formation of the tran8-tranm-acid in the animal body. The expense of this work was in part defrayed by a grant from the Medical Research Council. We are grateful to Prof. R. Cruickshan...

Electrophoresis of Proteins on Filter Paper

A simplified procedure for filter paper electrophoresis is described in which disturbing factors such as evaporation, heating, buffer concentration gradients, and pH changes in the electrode vessels were reduced to a minimum. Artificial mixtures of highly purified proteins could be separated and the components isolated. The application of the method to a variety of studies on serum proteins is ...

The electrophoresis of acid mucopolysaccharides on filter paper.

The use and limitations of filter-paper electrophoresis.

In 1935 Tiselius, using the apparatus he had devised in 1930, demonstrated that human serum globulin fell into three reasonably defined groups based on their electrophoretic mobilities. For the next 15 years a steady flood of papers reported the fluctuations of albumin and the globulins in young and old, in health and disease, as disclosed by analyses carried out using Tiselius apparatus with a...

Cyclodextrine Screening for the Chiral Separation of Carvedilol by Capillary Electrophoresis

Carvedilol is administered as a racemic mixture of the R(+)- and S(-)-enantiomers, although it was demonstrated that the two enantiomers exhibit different pharmacological effects and stereoselective pharmacokinetics. The aim of this study was the evaluation of several native and derivatized cyclodextrines as chiral selectors for the separation of carvedilol enantiomers. Stereoselective interact...